Clinical characteristics and risk factors analysis of amalgamative infection of liver cirrhosis with hepatic decompensation

Objectives: This study is to characterize the clinic symptoms and analyze the risk factors of amalgamative infection for LCHD. Methods: 224 LCHD cases were divided into infection group and non-infection group according to their infection history. SPSS l6 statistical software was utilized to analyze the possible risk factors by unconditioned Logistic regression analysis, and calculate the odds ratio (OR). Results: Among these 224 LCHD patients, 105 cases had infection (46.88%) mainly from community infection. Infection occurred mainly in the respiratory tract and abdominal cavity, followed by urinary tract, digestive tract, biliary tract, skin and soft tissue infections. The major nosocomial infection is intraperitoneal infection and the main community infection is respiratory tract infection. 19 cases of 41 patients with hospital infection had fever (46.34%). Routine blood white blood cells analysis revealed that fever was not significantly associated with leukocyte count. Conclusion: Liver cirrhosis with hepatic decompensation was mainly from community infection. Infection occurred mainly in the respiratory tract and abdominal cavity. Age, gastrointestinal bleeding, liver function grade C and hospital time all contributed to the infection of LCHD. Therefore, early detection and timely treatment of LCHD can reduce the incidence of infection and mortality.